You can store the value of the macro in a variable and add a variable breakpoint or if the macro ultimately stores the value at a physical address you can a memory watchpoint to monitor the value at the address.
To add a memory watchpoint:
From the PSoC Creator Debug menu, select New Breakpoint > Memory Watchpoint...
In the Breakpoints window New menu, select Watch Memory...
In a similar way you can also add a function or a variable breakpoint.